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Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4

In the earliest stages of antigen receptor assembly, D and J segments of the Ig heavy chain and T cell receptor β loci are recombined in B and T cells, respectively, whereas the V segments are not. Distinct distribution patterns of various histone modifications and the nucleosome-remodeling factor B...

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Autors principals: Morshead, Katrina B., Ciccone, David N., Taverna, Sean D., Allis, C. David, Oettinger, Marjorie A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC208800/
https://ncbi.nlm.nih.gov/pubmed/14500909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1932643100
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