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A nonconserved Ala401 in the yeast Rsp5 ubiquitin ligase is involved in degradation of Gap1 permease and stress-induced abnormal proteins

A toxic l-proline analogue, l-azetidine-2-carboxylic acid (AZC), causes misfolding of the proteins into which it is incorporated competitively with l-proline, thereby inhibiting the growth of the cells. AZC enters budding yeast Saccharomyces cerevisiae cells primarily through the general amino acid...

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Detalhes bibliográficos
Main Authors: Hoshikawa, Chikara, Shichiri, Mika, Nakamori, Shigeru, Takagi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC208788/
https://ncbi.nlm.nih.gov/pubmed/14500784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1933153100
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