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Gating and regulation of connexin 43 (Cx43) hemichannels

Connexin 43 (Cx43) nonjunctional or “unapposed” hemichannels can open under physiological or pathological conditions. We characterize hemichannels comprised of Cx43 or Cx43-EGFP (Cx43 with enhanced GFP fused to the C terminus) expressed in HeLa cells. Channel opening was induced at potentials greate...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Contreras, Jorge E., Sáez, Juan C., Bukauskas, Feliksas F., Bennett, Michael V. L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208767/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/13130072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1434298100
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