Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

Rat cortical astrocytes in pure culture are functionally coupled to neighboring cells via connexin (Cx) 43 gap junctions under ordinary conditions. Small fluorescent molecules such as Lucifer yellow (LY) pass between cell interiors via gap junctions, but do not enter the cells when externally applie...

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Bibliografske podrobnosti

izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Contreras, Jorge E., Sánchez, Helmut A., Eugenín, Eliseo A., Speidel, Dina, Theis, Martin, Willecke, Klaus, Bukauskas, Feliksas F., Bennett, Michael V. L., Sáez, Juan C.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2001
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.012589799
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