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Competing ligands stabilize alternate conformations of the energy coupling motif of a TonB-dependent outer membrane transporter
BtuB is a TonB-dependent outer-membrane transporter for vitamin B(12) (or cyanocobalamin, CN-Cbl) in Escherichia coli. The binding of CN-Cbl is believed to promote an unfolding or undocking of the Ton box, the conserved N-terminal energy coupling motif at the periplasmic surface of the transporter....
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2003
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC208766/ https://ncbi.nlm.nih.gov/pubmed/13679579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1932486100 |
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