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Competing ligands stabilize alternate conformations of the energy coupling motif of a TonB-dependent outer membrane transporter
BtuB is a TonB-dependent outer-membrane transporter for vitamin B(12) (or cyanocobalamin, CN-Cbl) in Escherichia coli. The binding of CN-Cbl is believed to promote an unfolding or undocking of the Ton box, the conserved N-terminal energy coupling motif at the periplasmic surface of the transporter....
Sparad:
| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC208766/ https://ncbi.nlm.nih.gov/pubmed/13679579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1932486100 |
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