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Role of residual structure in the unfolded state of a thermophilic protein

Ribonucleases H from the thermophilic bacterium Thermus thermophilus and the mesophile Escherichia coli demonstrate a dramatic and surprising difference in their change in heat capacity upon unfolding (ΔCp°). The lower ΔCp° of the thermophilic protein directly contributes to its higher thermal denat...

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Detalhes bibliográficos
Main Authors: Robic, Srebrenka, Guzman-Casado, Mercedes, Sanchez-Ruiz, Jose M., Marqusee, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC208759/
https://ncbi.nlm.nih.gov/pubmed/14504401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1635051100
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