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Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection
Both x-ray crystallography and chemical footprinting indicate that bases of the HIV type 1 (HIV-1) polypurine tract (PPT)-containing RNA/DNA hybrid deviate from standard Watson–Crick base pairing. However, the contribution of these structural anomalies to the accuracy of plus-strand primer selection...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC208748/ https://ncbi.nlm.nih.gov/pubmed/12972638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1932546100 |
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