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Inorganic polyphosphate stimulates mammalian TOR, a kinase involved in the proliferation of mammary cancer cells

Inorganic polyphosphate (poly P), chains of hundreds of phosphate residues linked by “high-energy” bonds as in ATP, has been conserved from prebiotic times in all cells. Poly P is essential for a wide variety of functions in bacteria, including virulence in pathogens. In this study, we observe the u...

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Hlavní autoři: Wang, Lihong, Fraley, Cresson D., Faridi, Jesika, Kornberg, Arthur, Roth, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC208743/
https://ncbi.nlm.nih.gov/pubmed/12970465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1534805100
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