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Septins Regulate Actin Organization and Cell Cycle Arrest Through SOCS7-Mediated Nuclear Accumulation of NCK
Mammalian septins are GTP-binding proteins the functions of which are not well understood. Knockdown of Sept2, 6, and 7 causes stress fibers to disintegrate and the cells to lose polarity. We now show that this phenotype is induced by nuclear accumulation of the adapter protein NCK, as the effects c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2085444/ https://ncbi.nlm.nih.gov/pubmed/17803907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.06.053 |
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