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Integration of linear and dendritic actin nucleation in Nck-induced actin comets

The Nck adaptor protein recruits cytosolic effectors such as N-WASP that induce localized actin polymerization. Experimental aggregation of Nck SH3 domains at the membrane induces actin comet tails—dynamic, elongated filamentous actin structures similar to those that drive the movement of microbial...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Borinskaya, Sofya, Velle, Katrina B., Campellone, Kenneth G., Talman, Arthur, Alvarez, Diego, Agaisse, Hervé, Wu, Yi I., Loew, Leslie M., Mayer, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713129/
https://ncbi.nlm.nih.gov/pubmed/26609071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-11-1555
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