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Gene replacement and expression of foreign DNA in mycobacteria.

A system that permits molecular genetic manipulation of mycobacteria was developed on the basis of the yeast paradigm of gene replacement by homologous recombination. A shuttle vector that can replicate autonomously at a high copy number in Escherichia coli but must integrate into homologous DNA for...

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Библиографические подробности
Главные авторы: Husson, R N, James, B E, Young, R A
Формат: Artigo
Язык:Inglês
Опубликовано: 1990
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC208472/
https://ncbi.nlm.nih.gov/pubmed/2153655
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