Gene replacement and expression of foreign DNA in mycobacteria.
A system that permits molecular genetic manipulation of mycobacteria was developed on the basis of the yeast paradigm of gene replacement by homologous recombination. A shuttle vector that can replicate autonomously at a high copy number in Escherichia coli but must integrate into homologous DNA for...
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| Veröffentlicht in: | J Bacteriol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1990
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.2.519-524.1990 |
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