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Epigenetic Inactivation of the Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Gene in Human Prostate Tumors

Gene silencing via CpG island methylation in the promoter region is one of the mechanisms by which tumor suppressor genes are inactivated in human cancers. Previous studies have shown that the TIMP-2 gene, which is an endogenous inhibitor of matrix metalloproteinases involved in cell invasion and tu...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Pulukuri, Sai MuraliKrishna, Patibandla, Sruthi, Patel, Jitendra, Estes, Norman, Rao, Jasti S.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084378/
https://ncbi.nlm.nih.gov/pubmed/17325663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210329
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