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Functional screening identifies miR-315 as a potent activator of Wingless signaling

The existence of vast regulatory networks mediated by microRNAs (miRNAs) suggests broad potential for miRNA dysfunction to contribute to disease. However, relatively few miRNA–target interactions are likely to make detectable contributions to phenotype, and effective strategies to identify these few...

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Detalhes bibliográficos
Main Authors: Silver, Serena J., Hagen, Joshua W., Okamura, Katsutomo, Perrimon, Norbert, Lai, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084312/
https://ncbi.nlm.nih.gov/pubmed/17989227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706673104
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