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A novel approach for imaging brain-behaviour relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator
Medically-refractory seizures cause inflammation and neurodegeneration. Seizure initiation thresholds have been linked in mice to the serine protease tissue plasminogen activator (tPA); mice lacking tPA exhibit resistance to seizure induction, and the ensuing inflammation and neurodegeneration are s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084071/ https://ncbi.nlm.nih.gov/pubmed/17707126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2007.06.032 |
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