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Cytoskeletal Signaling via α-Actinin-1 Mediates ERK1/2 Activation by Repetitive Deformation in Human Caco-2 Intestinal Epithelial Cells

BACKGROUND: Repetitive deformation stimulates proliferation in human Caco-2 intestinal epithelial cells via an ERK1/2-dependent pathway. We examined the effects of cytoskeletal perturbation on deformation-induced signaling in Caco-2 cells. METHODS: The Caco-2 cell cytoskeleton was disrupted with eit...

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Détails bibliographiques
Auteurs principaux: Craig, David H., Zhang, Jianhu, Basson, Marc D.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084063/
https://ncbi.nlm.nih.gov/pubmed/17936423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2007.08.001
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