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Recovery of cell cycle delay following targeted gene repair by oligonucleotides

We have previously shown that activation of the homologous recombinational repair pathway leads to a block of cell division in corrected cells, possibly through the activity of checkpoint proteins Chk1 and Chk2. In this study, we examine the long term impact of this stalling on the growth of cells t...

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Autores principales: Ferrara, Luciana, Engstrom, Julia U., Schwartz, Timothy, Parekh-Olmedo, Hetal, Kmiec, Eric B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083256/
https://ncbi.nlm.nih.gov/pubmed/17560837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.04.007
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