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MP4- and MOG:35–55-induced EAE in C57BL/6 mice differentially targets brain, spinal cord and cerebellum

Mechanism-oriented studies of EAE rely mostly on gene-modified mice on the C57BL/6 background. Here we report that MP4-induced EAE displays characteristic differences in CNS pathology as compared to MOG peptide 35–55-elicited disease. While in the latter, the topology of CNS infiltration remained un...

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Detaylı Bibliyografya
Asıl Yazarlar: Kuerten, Stefanie, Kostova-Bales, Dilyana A., Frenzel, Lukas P., Tigno, Justine T., Tary-Lehmann, Magdalena, Angelov, Doychin N., Lehmann, Paul V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083209/
https://ncbi.nlm.nih.gov/pubmed/17655940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.06.016
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