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A novel locus conferring fluoroquinolone resistance in Staphylococcus aureus.

Fluoroquinolones such as ciprofloxacin and ofloxacin are potent antimicrobial agents that antagonize the A subunit of DNA gyrase. We selected and mapped a novel fluoroquinolone resistance gene on the Staphylococcus aureus chromosome. Resistant mutants were selected with ciprofloxacin or ofloxacin an...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Trucksis, M, Wolfson, J S, Hooper, D C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208319/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1653224/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.18.5854-5860.1991
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