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A novel locus conferring fluoroquinolone resistance in Staphylococcus aureus.

Fluoroquinolones such as ciprofloxacin and ofloxacin are potent antimicrobial agents that antagonize the A subunit of DNA gyrase. We selected and mapped a novel fluoroquinolone resistance gene on the Staphylococcus aureus chromosome. Resistant mutants were selected with ciprofloxacin or ofloxacin an...

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Hlavní autoři: Trucksis, M, Wolfson, J S, Hooper, D C
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC208319/
https://ncbi.nlm.nih.gov/pubmed/1653224
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