Messenger RNA deadenylylation precedes decapping in mammalian cells

In yeast, the major mRNA degradation pathway is initiated by poly(A) tail shortening that triggers mRNA decapping. The mRNA is then degraded by 5′-to-3′ exonucleolysis. In mammalian cells, even though poly(A) tail shortening also precedes mRNA degradation, the degradation pathway has not been elucid...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Couttet, P., Fromont-Racine, M., Steel, D., Pictet, R., Grange, T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20829/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9159123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.11.5628
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