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Synergy between adjacent zinc fingers in sequence-specific DNA recognition

Zif268-like zinc fingers are generally regarded as independent DNA-binding modules that each specify three base pairs in adjacent, but discrete, subsites. However, crystallographic evidence suggests that a contact also can occur from the second helical position of one finger to the subsite of the pr...

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Autori principali: Isalan, Mark, Choo, Yen, Klug, Aaron
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20827/
https://ncbi.nlm.nih.gov/pubmed/9159121
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