BRCA1 is a component of the RNA polymerase II holoenzyme

The familial breast–ovarian tumor suppressor gene product BRCA1 was found to be a component of the RNA polymerase II holoenzyme by several criteria. BRCA1 was found to copurify with the holoenzyme over multiple chromatographic steps. Other tested transcription activators that could potentially conta...

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Bibliografiska uppgifter
Huvudupphovsmän: Scully, Ralph, Anderson, Stephen F., Chao, David M., Wei, Wanjiang, Ye, Liyan, Young, Richard A., Livingston, David M., Parvin, Jeffrey D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC20825/
https://ncbi.nlm.nih.gov/pubmed/9159119
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