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Bile salt–dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans

Bile salt–dependent lipase (BSDL) is an enzyme involved in the duodenal hydrolysis and absorption of cholesteryl esters. Although some BSDL is transported to blood, the role of circulating BSDL is unknown. Here, we demonstrate that BSDL is stored in platelets and released upon platelet activation. B...

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Detalhes bibliográficos
Main Authors: Panicot-Dubois, Laurence, Thomas, Grace M., Furie, Barbara C., Furie, Bruce, Lombardo, Dominique, Dubois, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2082148/
https://ncbi.nlm.nih.gov/pubmed/18037996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32655
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