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Bile salt–dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans
Bile salt–dependent lipase (BSDL) is an enzyme involved in the duodenal hydrolysis and absorption of cholesteryl esters. Although some BSDL is transported to blood, the role of circulating BSDL is unknown. Here, we demonstrate that BSDL is stored in platelets and released upon platelet activation. B...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2082148/ https://ncbi.nlm.nih.gov/pubmed/18037996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32655 |
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