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Anti-Amyloid Beta Protein Antibody Passage Across the Blood-Brain Barrier in the SAMP8 Mouse Model of Alzheimer's Disease: An Age-related Selective Uptake with Reversal of Learning Impairment
Amyloid beta protein (Aβ) levels are elevated in the brain of Alzheimer's disease patients. Anti-Aβ antibodies can reverse the histologic and cognitive impairments in mice which overexpress Aβ. Passive immunization appears safer than vaccination and treatment of patients will likely require hum...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080786/ https://ncbi.nlm.nih.gov/pubmed/17582399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.05.005 |
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