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Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined–induced fit mechanism
All known guanine-sensing riboswitches regulate gene expression by specifically binding to guanine (G) or related analogs with high affinity to switch off transcription. The aptamers of this class of riboswitches are characterized by three helices (P1–P3), surrounding a central core of phylogenetica...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080608/ https://ncbi.nlm.nih.gov/pubmed/17959930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.635307 |
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