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Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNA

RNA unfolding and folding reactions in physiological conditions can be facilitated by mechanical force one molecule at a time. By using force-measuring optical tweezers, we studied the mechanical unfolding and folding of a hairpin-type pseudoknot in human telomerase RNA in a near-physiological solut...

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Hlavní autoři: Chen, Gang, Wen, Jin-Der, Tinoco, Ignacio
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080604/
https://ncbi.nlm.nih.gov/pubmed/17959928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.676707
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