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Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNA
RNA unfolding and folding reactions in physiological conditions can be facilitated by mechanical force one molecule at a time. By using force-measuring optical tweezers, we studied the mechanical unfolding and folding of a hairpin-type pseudoknot in human telomerase RNA in a near-physiological solut...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080604/ https://ncbi.nlm.nih.gov/pubmed/17959928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.676707 |
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