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Thiostrepton inhibition of tRNA delivery to the ribosome

Ribosome-stimulated hydrolysis of guanosine-5′-triphosphate (GTP) by guanosine triphosphatase (GTPase) translation factors drives protein synthesis by the ribosome. Allosteric coupling of GTP hydrolysis by elongation factor Tu (EF-Tu) at the ribosomal GTPase center to messenger RNA (mRNA) codon:amin...

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Autori principali: Gonzalez, Ruben L., Chu, Steven, Puglisi, Joseph D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080598/
https://ncbi.nlm.nih.gov/pubmed/17951333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.499407
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