Resistance to apoptosis, increased growth potential, and altered gene expression in cells that survived genotoxic hexavalent chromium [Cr(VI)] exposure

Certain hexavalent chromium [Cr(VI)] compounds are known genotoxic respiratory carcinogens, which induce apoptosis as a predominant mode of cell death. Selection of cells that are resistant to apoptosis may be a factor in tumour progression. We developed sub-populations of telomerase-transfected hum...

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Auteurs principaux: Pritchard, Daryl E., Ceryak, Susan, Ramsey, Keri E., O’Brien, Travis J., Ha, Linan, Fornsaglio, Jamie L., Stephan, Dietrich A., Patierno, Steven R.
Format: Artigo
Langue:Inglês
Publié: 2005
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080352/
https://ncbi.nlm.nih.gov/pubmed/16283527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-005-8292-2
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