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Regulation of the expression of the tissue transglutaminase gene by DNA methylation

We have investigated the role of DNA methylation in the regulation of the expression of the human tissue transglutaminase gene. Studies on the methylation of the transglutaminase promoter in normal and neoplastic human cells demonstrated that the promoter is methylated in vivo and hypomethylation of...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lu, Shan, Davies, Peter J. A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9114053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4692
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