Tissue-specific methylation of human insulin gene and PCR assay for monitoring beta cell death.
The onset of metabolic dysregulation in type 1 diabetes (T1D) occurs after autoimmune destruction of the majority of pancreatic insulin-producing beta cells. We previously demonstrated that the DNA encoding the insulin gene is uniquely unmethylated in these cells and then developed a methylation-spe...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2014-01-01
|
| Colección: | PLoS ONE |
| Acceso en línea: | http://europepmc.org/articles/PMC3983232?pdf=render |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|