Iron Chelators ICL670 and 311 Inhibit HIV-1 Transcription

HIV-1 replication is induced by the excess of iron and iron chelation by desferrioxamine (DFO) inhibits viral replication by reducing proliferation of infected cells. Treatment of the cells with DFO and 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone (311) inhibit expression of proteins that re...

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Main Authors: Debebe, Zufan, Ammosova, Tatyana, Jerebtsova, Marina, Kurantsin-Mills, Joseph, Niu, Xiaomei, Charles, Sharroya, Richardson, Des R., Ray, Patricio E., Gordeuk, Victor R., Nekhai, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077891/
https://ncbi.nlm.nih.gov/pubmed/17631934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.06.011
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