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Recombination Mediator and Rad51 Targeting Activities of a Human BRCA2 Polypeptide
BRCA2 likely exerts its tumor suppressor function by enhancing the efficiency of the homology-directed repair of injured chromosomes. To help define the DNA repair role of BRCA2, we expressed and purified a polypeptide, BRC3/4-DBD, that harbors its BRC3 and BRC4 repeats and DNA binding domain. BRC3/...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2077811/ https://ncbi.nlm.nih.gov/pubmed/16513631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M601249200 |
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