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Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages

Macrophage-derived foam cells express apolipoprotein E (apoE) abundantly in atherosclerotic lesions. To examine the physiologic role of apoE secretion by the macrophage in atherogenesis, bone marrow transplantation was used to reconstitute C57BL/6 mice with macrophages that were either null or wild...

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Main Authors: Fazio, Sergio, Babaev, Vladimir R., Murray, Alisa B., Hasty, Alyssa H., Carter, Kathy J., Gleaves, Linda A., Atkinson, James B., Linton, MacRae F.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences of the USA 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC20778/
https://ncbi.nlm.nih.gov/pubmed/9114045
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