Multiple determinants of functional mRNA stability: sequence alterations at either end of the lacZ gene affect the rate of mRNA inactivation.
The Escherichia coli lacZ gene was used as a model system to identify specific sequence elements affecting mRNA stability. Various insertions and substitutions at the ribosome-binding site increased or decreased the rate of mRNA inactivation by up to fourfold. Deletion of a dyad symmetry, which may...
Sparad:
| I publikationen: | J Bacteriol |
|---|---|
| Huvudupphov: | |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
American Society for Microbiology (ASM)
1991
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1706700/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.7.2167-2172.1991 |
| Taggar: |
Inga taggar, Lägg till första taggen!
|