Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin Agene

We reported previously that homocysteine (Hcy) inhibits endothelial cell (EC) growth by transcriptional inhibition of the cyclin A gene via a hypomethylation-related mechanism. In this study, we examined the effect of Hcy on epigenetic modification of the cyclin A gene and its biologic role in human...

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Bibliografiska uppgifter
Huvudupphovsmän: Jamaluddin, Md S., Chen, Irene, Yang, Fan, Jiang, Xiaohua, Jan, Michael, Liu, Xiaoming, Schafer, Andrew I., Durante, William, Yang, Xiaofeng, Wang, Hong
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2007
Ämnen:
Hemostasis, Thrombosis, and Vascular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077313/
https://ncbi.nlm.nih.gov/pubmed/17698632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-096701
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