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Reconstitution of a branch of the Manduca sexta prophenoloxidase activation cascade in vitro: Snake-like hemolymph proteinase 21 (HP21) cleaved by HP14 activates prophenoloxidase-activating proteinase-2 precursor

Upon wounding or infection, a serine proteinase cascade in insect hemolymph leads to prophenoloxidase (proPO) activation and melanization, a defense response against invading microbes. In the tobacco hornworm Manduca sexta, this response is initiated via hemolymph proteinase 14 (HP14), a mosaic prot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yang, Jiang, Haobo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077082/
https://ncbi.nlm.nih.gov/pubmed/17785189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2007.05.013
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