BARD1 Participates with BRCA1 in Homology-Directed Repair of Chromosome Breaks

The BRCA1 tumor suppressor has been implicated in the maintenance of chromosomal stability through homology-directed repair of DNA double-strand breaks. Much of the BRCA1 in cells forms a heterodimeric complex with a structurally related protein BARD1. We report that expression of truncated mouse or...

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Hlavní autoři: Westermark, Ulrica K., Reyngold, Marsha, Olshen, Adam B., Baer, Richard, Jasin, Maria, Moynahan, Mary Ellen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
DNA Dynamics and Chromosome Structure
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC207645/
https://ncbi.nlm.nih.gov/pubmed/14560035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7926-7936.2003
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