AlgR-binding sites within the algD promoter make up a set of inverted repeats separated by a large intervening segment of DNA.

Activation of algD by AlgR is essential for mucoidy, a virulence factor expressed by Pseudomonas aeruginosa in cystic fibrosis. Two AlgR-binding sites, RB1 and RB2, located far upstream from the algD mRNA start site, are essential for the high-level activity of algD. However, the removal of RB1 and...

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Dettagli Bibliografici

Pubblicato in:	J Bacteriol
Autori principali:	Mohr, C D, Leveau, J H, Krieg, D P, Hibler, N S, Deretic, V
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1400214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.20.6624-6633.1992
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