AlgR-binding sites within the algD promoter make up a set of inverted repeats separated by a large intervening segment of DNA.

Activation of algD by AlgR is essential for mucoidy, a virulence factor expressed by Pseudomonas aeruginosa in cystic fibrosis. Two AlgR-binding sites, RB1 and RB2, located far upstream from the algD mRNA start site, are essential for the high-level activity of algD. However, the removal of RB1 and...

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Détails bibliographiques
Auteurs principaux: Mohr, C D, Leveau, J H, Krieg, D P, Hibler, N S, Deretic, V
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC207638/
https://ncbi.nlm.nih.gov/pubmed/1400214
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