Fibroblast Growth Factor 2-Mediated Translational Control of IAPs Blocks Mitochondrial Release of Smac/DIABLO and Apoptosis in Small Cell Lung Cancer Cells

The mitochondrial release of cytochrome c and Smac/DIABLO has been implicated in the activation of apoptosis in response to cell stress. Smac promotes cytochrome c-induced activation of caspases by sequestering the inhibitor of apoptosis protein (IAP) family of potent caspase suppressors. Differenti...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Pardo, Olivier E., Lesay, Adeline, Arcaro, Alexandre, Lopes, Rita, Ng, Bee Ling, Warne, Patricia H., McNeish, Iain A., Tetley, Teresa D., Lemoine, Nicholas R., Mehmet, Huseyin, Seckl, Michael J., Downward, Julian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14560006/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.21.7600-7610.2003
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