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Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling

The Src homology 2-containing phosphotyrosine phosphatase (SHP2) is primarily a positive effector of receptor tyrosine kinase signaling. However, the molecular mechanism by which SHP2 effects its biological function is unknown. In this report, we provide evidence that defines the molecular mechanism...

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Hlavní autoři: Agazie, Yehenew M., Hayman, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC207628/
https://ncbi.nlm.nih.gov/pubmed/14560030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7875-7886.2003
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