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Evidence of reciprocity of bcl-2 and p53 expression in human colorectal adenomas and carcinomas.

Evidence of accumulating for the failure of apoptosis as an important factor in the evolution of colorectal cancer and its poor response to adjuvant therapy. The proto-oncogene bcl-2 suppresses apoptosis. Its expression could provide an important survival advantage permitting the development of colo...

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Autori principali: Watson, A. J., Merritt, A. J., Jones, L. S., Askew, J. N., Anderson, E., Becciolini, A., Balzi, M., Potten, C. S., Hickman, J. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075819/
https://ncbi.nlm.nih.gov/pubmed/8611422
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