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The spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas

Background: p53 mutations are frequently observed in colorectal carcinomas but they have also been found in colorectal adenomas, although considerably less frequently. Aims: To explore p53 mutations in benign tumours, we have screened 70 colorectal adenomas for allelic loss at, and point mutations i...

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Detalhes bibliográficos
Main Authors: Hao, X P, Frayling, I M, Sgouros, J G, Du, M Q, Willcocks, T C, Talbot, I C, Tomlinson, I P M
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2002 by Gut 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773253/
https://ncbi.nlm.nih.gov/pubmed/12010886
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