Accelerated Fat Absorption in Intestinal Alkaline Phosphatase Knockout Mice

Intestinal alkaline phosphatase (IAP) is the most ancestral of the tissue-specific members of the AP gene family. Several studies have suggested an absorptive function for IAP, but in vivo data to this effect have been lacking. We inactivated the mouse IAP gene in embryo-derived stem cells and gener...

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Главные авторы: Narisawa, Sonoko, Huang, Lei, Iwasaki, Arata, Hasegawa, Hideaki, Alpers, David H., Millán, José Luis
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
Предметы:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC207564/
https://ncbi.nlm.nih.gov/pubmed/14560000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7525-7530.2003
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