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Human Homologues of a Borrelia T cell Epitope Associated with Antibiotic-Refractory Lyme Arthritis

Antibiotic-refractory Lyme arthritis, which may result from infection-induced autoimmunity, is associated with HLA-DR molecules that bind an epitope of Borrelia burgdorferi (Bb) outer-surface protein A (OspA(165−173)) and with T cell reactivity with this epitope. One potential mechanism to explain t...

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Detalhes bibliográficos
Main Authors: Drouin, Elise E., Glickstein, Lisa, Kwok, William W., Nepom, Gerald T., Steere, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075570/
https://ncbi.nlm.nih.gov/pubmed/17555819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.04.017
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