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Relationship between Immunity to Borrelia burgdorferi Outer-surface Protein A (OspA) and Lyme Arthritis

Antibiotic-refractory Lyme arthritis may result from Borrelia burgdorferi–induced autoimmunity in affected joints. Such patients usually have certain HLA-DRB1 molecules that bind an epitope of B. burgdorferi outer-surface protein A (OspA(163–175)), and cellular and humoral immune responses to OspA a...

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Detalhes bibliográficos
Main Authors: Steere, Allen C., Drouin, Elise E., Glickstein, Lisa J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106239/
https://ncbi.nlm.nih.gov/pubmed/21217173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciq117
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