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Recruitment of apical dendritic T-type Ca(2+) channels by backpropagating spikes underlies de novo intrinsic bursting in hippocampal epileptogenesis
A single episode of status epilepticus (se) induced in rodents by the convulsant pilocarpine, produces, after a latent period of ≥ 2 weeks, a chronic epileptic condition. During the latent period of epileptogenesis, most CA1 pyramidal cells that normally fire in a regular pattern, acquire low-thresh...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2075546/ https://ncbi.nlm.nih.gov/pubmed/17272342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.127670 |
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